The Promise of Intra-Ovarian Platelet-Rich Plasma (PRP) for Ovarian Rejuvenation

Dr. Marika Raff • September 18, 2025

A Promising Approach for Women with Diminished Ovarian Reserve or Early Ovarian Aging

At Caperton Fertility Institute, our team is dedicated to offering patients the latest advances in reproductive medicine. One of the most promising emerging treatments we are exploring is intra-ovarian platelet-rich plasma (PRP) therapy, sometimes referred to as ovarian rejuvenation.


This innovative approach may provide new hope for women facing diminished ovarian reserve or early ovarian aging, helping them regain options on their fertility journey.


What Is Platelet-Rich Plasma (PRP)?

Platelet-rich plasma (PRP) is a concentrate of platelets derived from a patient’s own blood. Platelets are naturally rich in growth factors—proteins that stimulate healing, repair, and regeneration of tissue.

PRP has been widely used in:


  • Orthopedics (joint healing, tissue repair)
  • Dermatology (skin regeneration)
  • Sports medicine (injury recovery)


Now, these same regenerative principles are being applied in reproductive medicine to support ovarian health.


How Does Intra-Ovarian PRP Work?

The intra-ovarian PRP procedure involves:

  1. Drawing a small blood sample from the patient
  2. Processing the blood to isolate PRP
  3. Carefully injecting PRP into the ovaries using ultrasound guidance


Potential benefits of ovarian PRP may include:

  • Stimulating dormant ovarian follicles
  • Improving blood flow within the ovary
  • Supporting development of higher-quality eggs
  • Potentially restoring hormone production in women with early ovarian decline


While PRP is still considered experimental, initial studies and clinical reports show encouraging signs that it may improve ovarian function in select patients.


Who Might Benefit From Ovarian PRP?

Ovarian PRP therapy may be considered for women with:


  • Diminished ovarian reserve (low AMH or high FSH levels)
  • Premature ovarian insufficiency (POI) or early menopause
  • A poor response to IVF stimulation in the past
  • Age-related decline in ovarian function and delayed fertility goals


⚠️ Important Note: PRP is not a cure for infertility, and not every patient is an ideal candidate. At Caperton Fertility Institute, we take a highly individualized approach to determine if PRP could be beneficial for your unique situation.


What Does the Research Say About Ovarian PRP?

The use of intra-ovarian PRP is still investigational, and more large-scale clinical trials are needed. However, early studies suggest some women may experience:


  • Improved hormone levels (FSH, AMH, estrogen)
  • Return of menstrual cycles in cases of ovarian insufficiency
  • Increased number of eggs retrieved during IVF cycles


These findings provide hope, but it is essential to set realistic expectations. PRP is not yet a standard fertility treatment, and outcomes vary from patient to patient.


The Caperton Fertility Institute Approach

At Caperton Fertility Institute in Albuquerque, NM, and El Paso, TX, we are committed to bringing safe, evidence-based innovations to our patients.

For women exploring ovarian rejuvenation with PRP, we offer:

  • Compassionate counseling
  • Thorough fertility evaluation
  • Access to emerging therapies within the context of advanced fertility care


Our goal is to maximize your chances of success—whether that involves IVF, egg freezing, or ovarian PRP therapy.


Is Ovarian PRP Right for You?

If you are struggling with:

  • Diminished ovarian reserve
  • Premature ovarian insufficiency (POI)
  • Past IVF challenges or poor ovarian response


…then ovarian PRP may be worth discussing with your fertility specialist. Every patient’s fertility journey is unique, and our team is here to help you explore your best options with clarity and hope.


Next Steps

At Caperton Fertility Institute, we combine cutting-edge science with compassionate care. If you are interested in learning more about ovarian rejuvenation with PRP or other fertility treatments, we invite you to schedule a consultation today.


📍 Locations in Albuquerque, NM, and El Paso, TX
📞 Call us now or request an appointment online to explore whether ovarian PRP therapy could be part of your fertility plan.

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Understanding Fibroids and Fertility

By Dr. Lee Caperton • October 7, 2025
Uterine fibroids are a common diagnosis among women of reproductive age. While many fibroids are harmless and cause no symptoms, others can interfere with fertility and pregnancy. At Caperton Fertility Institute , we help patients understand how fibroids may affect reproductive health and provide personalized treatment options to optimize fertility outcomes. What Are Uterine Fibroids? Fibroids, also known as leiomyomas , are benign (non-cancerous) growths that develop in or on the uterus. They can vary greatly in size, number, and location. Depending on where they form, fibroids are classified into several types: Submucosal Fibroids: Grow into the uterine cavity Intramural Fibroids: Develop within the uterine wall Subserosal Fibroids: Form on the outer surface of the uterus Pedunculated Fibroids: Attached by a stalk extending from the uterus How Fibroids Can Affect Fertility Not all fibroids impact fertility. However, certain types and locations are more likely to interfere with conception, implantation, or pregnancy progression. Submucosal Fibroids: These are most likely to affect fertility because they distort the uterine cavity, which can prevent implantation or increase the risk of miscarriage. Intramural Fibroids: When large, these fibroids can change the shape of the uterus and affect blood flow, potentially reducing the chances of successful embryo implantation. Tubal Blockage: Fibroids located near the fallopian tubes can obstruct sperm or egg movement, preventing fertilization. Cervical Fibroids: Although rare, fibroids near the cervix can hinder sperm entry into the uterus. Common Symptoms of Fibroids Fibroid symptoms vary widely — some people experience significant discomfort, while others have no symptoms at all. Common signs include: Heavy or prolonged menstrual bleeding Pelvic pain or pressure Pain during intercourse Frequent urination or constipation Recurrent pregnancy loss or difficulty conceiving For many patients, fibroids are first discovered during a fertility evaluation or routine pelvic exam . Diagnosis and Treatment Options At Caperton Fertility Institute , we use advanced diagnostic imaging such as ultrasound and MRI to assess fibroid size, number, and location. Once diagnosed, treatment is tailored to your fertility goals and overall health. Treatment options include: Medical Management: Hormonal therapies to reduce symptoms and fibroid growth. Surgical Options: Myomectomy to remove fibroids while preserving the uterus. Minimally Invasive Procedures: Hysteroscopic or laparoscopic surgery for faster recovery and minimal scarring. Our approach is designed to preserve fertility whenever possible while alleviating symptoms and improving uterine health. Hope After a Fibroid Diagnosis A fibroid diagnosis doesn’t mean you can’t conceive. Many patients with fibroids go on to achieve healthy pregnancies — especially with proper evaluation and treatment. At Caperton Fertility Institute , our experienced fertility specialists in Albuquerque, NM , and El Paso, TX , provide compassionate, individualized care for every patient. We’ll guide you through diagnosis, treatment, and the next steps toward achieving your dream of parenthood. ✨ If you suspect fibroids may be affecting your fertility, schedule a consultation today. Let’s take the next step together toward your fertility goals.

Honoring Pregnancy & Infant Loss Awareness Month 🤍

By Dr. Marika Raff • October 7, 2025
Every loss is unique. Every story matters. Every life is remembered.
Blonde woman in red sweater smiles while using a laptop and tablet at a cafe table.

Egg Donor FAQ

By Dr. Kelly Caperton • September 19, 2025
1. What is egg donation? Egg donation is the process by which a healthy woman donates her eggs to help another individual or couple conceive a child. These eggs may be fertilized through in vitro fertilization (IVF) and implanted into a recipient’s uterus or frozen for future use. 2. Who can become an egg donor? At Caperton Fertility Institute, we welcome egg donors who meet the following criteria: Ages 19–30 Physically and emotionally healthy Non-smoker, non-drug user Regular menstrual cycles No history of genetic or reproductive disorders Willing to undergo medical and psychological screening Able to commit to the time and responsibilities of the donation process 3. Why do people need egg donors? Egg donors help individuals and couples who are unable to conceive using their own eggs due to: Advanced maternal age Genetic conditions Medical treatments like chemotherapy LGBTQ+ family-building Unexplained infertility 4. Is egg donation safe? Yes. Egg donation is a common and generally safe medical process. It involves hormone injections to stimulate the ovaries and a minor outpatient procedure to retrieve the eggs. Risks are low but can include mild discomfort, bloating, or temporary side effects from medication. Serious complications are rare. 5. Will donating affect my fertility? No, egg donation does not impact your long-term fertility. Women are born with thousands of eggs, and donation uses only a small number that would naturally be lost in a normal cycle. 6. Is egg donation painful? Most donors report mild discomfort similar to menstrual cramps. The egg retrieval procedure is done under light sedation, so you won’t feel pain during the process. Recovery typically takes 1–2 days. 7. Will I be compensated? Yes. Caperton Fertility Institute offers generous, ethically guided compensation for your time, effort, and commitment. The amount is discussed during your initial consultation and complies with all legal and medical guidelines. 8. How long is the egg donation process? The process generally takes 6–10 weeks from initial screening to egg retrieval. It includes: Application and screening Medical and psychological evaluations Legal review Hormonal stimulation (approx. 10–14 days) Egg retrieval procedure 9. Can I still work or go to school during the donation process? Yes. Most of the process can be scheduled around your routine. However, you'll need to attend several clinic appointments and take medications on a strict schedule. During the last week, you'll need to reduce physical activity. 10. Will my identity be kept confidential? Absolutely. Donor confidentiality is strictly maintained. You can choose to remain anonymous, open, or semi-open, depending on your preferences and the recipient’s needs. 11. How do I get started? To begin the egg donor application process: Visit our Portal Fill out a questionnaire Our donor coordinator will contact you for next steps 12. Can I donate more than once? Yes, eligible donors can donate up to six times, as recommended by the American Society for Reproductive Medicine (ASRM). Each cycle is spaced out for your health and safety.
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