The Impact of Weight Loss on Fertility: Exploring the Role of GLP-1 Agonists

Dr. Kelly Caperton • September 18, 2025

Understanding the Role of GLP-1 Agonists in Preconception Health and IVF Success

Weight plays a critical role in reproductive health. Both overweight and underweight individuals may face challenges when trying to conceive, but for many patients struggling with obesity, even modest weight loss can significantly improve fertility outcomes.


At Caperton Fertility Institute, with clinics in Albuquerque, NM, and El Paso, TX, we recognize the potential of new weight-loss therapies—such as GLP-1 receptor agonists—to support fertility and reproductive goals.


How Weight Affects Fertility

Excess body weight can affect fertility in multiple ways:

  • Hormonal Imbalances – Obesity can disrupt the hypothalamic-pituitary-ovarian axis, leading to irregular menstrual cycles and ovulation problems.
  • Insulin Resistance – Common in individuals with a higher BMI, insulin resistance can interfere with ovulation and increase the risk of polycystic ovary syndrome (PCOS).
  • Inflammation – Excess fat tissue produces inflammatory markers that may reduce egg quality, embryo development, and implantation success.
  • Male Fertility – Elevated BMI in men is linked to lower testosterone, reduced sperm quality, and decreased libido.


👉 Even a 5–10% reduction in body weight can restore ovulation and improve the chances of natural conception or success with fertility treatments like IUI and IVF.


What Are GLP-1 Agonists?

GLP-1 (glucagon-like peptide-1) receptor agonists are a class of medications originally developed to treat type 2 diabetes. They mimic the natural GLP-1 hormone, which helps regulate blood sugar and appetite.

Common GLP-1 medications include:


  • Semaglutide (Ozempic®, Wegovy®)
  • Liraglutide (Saxenda®)


These medications have shown remarkable weight loss results in people with and without diabetes, making them a valuable tool for patients preparing for pregnancy.


Benefits of GLP-1 Agonists for Fertility

For patients struggling with obesity or PCOS, GLP-1 medications may support fertility by:


  • Promoting sustainable weight loss
  • Improving insulin sensitivity
  • Helping regulate menstrual cycles
  • Reducing symptoms of PCOS
  • Lowering systemic inflammation


As part of a preconception health plan, GLP-1 therapy may help create a healthier environment for conception and pregnancy.


Considerations for Using GLP-1 Agonists in Fertility Treatment

It’s important to use GLP-1 medications under the guidance of a fertility specialist. Key considerations include:


  • Timing – GLP-1 agonists should generally be discontinued before trying to conceive, since safety in pregnancy has not yet been fully established.
  • Medical Supervision – Safe and effective use requires oversight, often in combination with nutrition counseling and lifestyle changes.
  • Individualized Plans – Not every patient is an ideal candidate. A comprehensive metabolic and fertility evaluation can help determine the best course of action.


Weight Loss as a Path to Parenthood

Weight loss isn’t just about numbers on the scale—it’s about optimizing your body for a healthy pregnancy.

At Caperton Fertility Institute, we believe in a holistic, evidence-based approach to weight and fertility, combining:


  • Advanced reproductive technologies (IUI, IVF, egg freezing)
  • Metabolic health strategies
  • The latest innovations like GLP-1 therapies


Together, these tools can help patients achieve better fertility outcomes and increase their chances of bringing home a healthy baby.


Next Steps: GLP-1 Agonists and Fertility Support

If you are struggling with weight and fertility challenges or are interested in learning whether GLP-1 medications (Ozempic®, Wegovy®, Saxenda®) could play a role in your fertility journey, our team is here to help.



📍 Caperton Fertility Institute – Albuquerque, NM & El Paso, TX
📞 Call today or request your consultation online to explore personalized fertility solutions tailored to your health and family goals.

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Understanding Fibroids and Fertility

By Dr. Lee Caperton • October 7, 2025
Uterine fibroids are a common diagnosis among women of reproductive age. While many fibroids are harmless and cause no symptoms, others can interfere with fertility and pregnancy. At Caperton Fertility Institute , we help patients understand how fibroids may affect reproductive health and provide personalized treatment options to optimize fertility outcomes. What Are Uterine Fibroids? Fibroids, also known as leiomyomas , are benign (non-cancerous) growths that develop in or on the uterus. They can vary greatly in size, number, and location. Depending on where they form, fibroids are classified into several types: Submucosal Fibroids: Grow into the uterine cavity Intramural Fibroids: Develop within the uterine wall Subserosal Fibroids: Form on the outer surface of the uterus Pedunculated Fibroids: Attached by a stalk extending from the uterus How Fibroids Can Affect Fertility Not all fibroids impact fertility. However, certain types and locations are more likely to interfere with conception, implantation, or pregnancy progression. Submucosal Fibroids: These are most likely to affect fertility because they distort the uterine cavity, which can prevent implantation or increase the risk of miscarriage. Intramural Fibroids: When large, these fibroids can change the shape of the uterus and affect blood flow, potentially reducing the chances of successful embryo implantation. Tubal Blockage: Fibroids located near the fallopian tubes can obstruct sperm or egg movement, preventing fertilization. Cervical Fibroids: Although rare, fibroids near the cervix can hinder sperm entry into the uterus. Common Symptoms of Fibroids Fibroid symptoms vary widely — some people experience significant discomfort, while others have no symptoms at all. Common signs include: Heavy or prolonged menstrual bleeding Pelvic pain or pressure Pain during intercourse Frequent urination or constipation Recurrent pregnancy loss or difficulty conceiving For many patients, fibroids are first discovered during a fertility evaluation or routine pelvic exam . Diagnosis and Treatment Options At Caperton Fertility Institute , we use advanced diagnostic imaging such as ultrasound and MRI to assess fibroid size, number, and location. Once diagnosed, treatment is tailored to your fertility goals and overall health. Treatment options include: Medical Management: Hormonal therapies to reduce symptoms and fibroid growth. Surgical Options: Myomectomy to remove fibroids while preserving the uterus. Minimally Invasive Procedures: Hysteroscopic or laparoscopic surgery for faster recovery and minimal scarring. Our approach is designed to preserve fertility whenever possible while alleviating symptoms and improving uterine health. Hope After a Fibroid Diagnosis A fibroid diagnosis doesn’t mean you can’t conceive. Many patients with fibroids go on to achieve healthy pregnancies — especially with proper evaluation and treatment. At Caperton Fertility Institute , our experienced fertility specialists in Albuquerque, NM , and El Paso, TX , provide compassionate, individualized care for every patient. We’ll guide you through diagnosis, treatment, and the next steps toward achieving your dream of parenthood. ✨ If you suspect fibroids may be affecting your fertility, schedule a consultation today. Let’s take the next step together toward your fertility goals.

Honoring Pregnancy & Infant Loss Awareness Month 🤍

By Dr. Marika Raff • October 7, 2025
Every loss is unique. Every story matters. Every life is remembered.
Blonde woman in red sweater smiles while using a laptop and tablet at a cafe table.

Egg Donor FAQ

By Dr. Kelly Caperton • September 19, 2025
1. What is egg donation? Egg donation is the process by which a healthy woman donates her eggs to help another individual or couple conceive a child. These eggs may be fertilized through in vitro fertilization (IVF) and implanted into a recipient’s uterus or frozen for future use. 2. Who can become an egg donor? At Caperton Fertility Institute, we welcome egg donors who meet the following criteria: Ages 19–30 Physically and emotionally healthy Non-smoker, non-drug user Regular menstrual cycles No history of genetic or reproductive disorders Willing to undergo medical and psychological screening Able to commit to the time and responsibilities of the donation process 3. Why do people need egg donors? Egg donors help individuals and couples who are unable to conceive using their own eggs due to: Advanced maternal age Genetic conditions Medical treatments like chemotherapy LGBTQ+ family-building Unexplained infertility 4. Is egg donation safe? Yes. Egg donation is a common and generally safe medical process. It involves hormone injections to stimulate the ovaries and a minor outpatient procedure to retrieve the eggs. Risks are low but can include mild discomfort, bloating, or temporary side effects from medication. Serious complications are rare. 5. Will donating affect my fertility? No, egg donation does not impact your long-term fertility. Women are born with thousands of eggs, and donation uses only a small number that would naturally be lost in a normal cycle. 6. Is egg donation painful? Most donors report mild discomfort similar to menstrual cramps. The egg retrieval procedure is done under light sedation, so you won’t feel pain during the process. Recovery typically takes 1–2 days. 7. Will I be compensated? Yes. Caperton Fertility Institute offers generous, ethically guided compensation for your time, effort, and commitment. The amount is discussed during your initial consultation and complies with all legal and medical guidelines. 8. How long is the egg donation process? The process generally takes 6–10 weeks from initial screening to egg retrieval. It includes: Application and screening Medical and psychological evaluations Legal review Hormonal stimulation (approx. 10–14 days) Egg retrieval procedure 9. Can I still work or go to school during the donation process? Yes. Most of the process can be scheduled around your routine. However, you'll need to attend several clinic appointments and take medications on a strict schedule. During the last week, you'll need to reduce physical activity. 10. Will my identity be kept confidential? Absolutely. Donor confidentiality is strictly maintained. You can choose to remain anonymous, open, or semi-open, depending on your preferences and the recipient’s needs. 11. How do I get started? To begin the egg donor application process: Visit our Portal Fill out a questionnaire Our donor coordinator will contact you for next steps 12. Can I donate more than once? Yes, eligible donors can donate up to six times, as recommended by the American Society for Reproductive Medicine (ASRM). Each cycle is spaced out for your health and safety.
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